High-Science, High-Touch
Wheeler Bio is a biologics CDMO specializing in antibody-based therapeutics, offering services from discovery through cGMP clinical supply.
Contact UsThe Wheeler Difference
High-Science, High-Touch describes the scientific rigor and client-focused partnership we apply to every program we work on. Our signature ModularCMC™ framework creates flexibility for phase-appropriate CMC development that streamlines the advancement of antibody-based therapeutics.
Gene to Clinic in 10 Months
High-Science – Wheeler Bio leverages its AI/ML-enabled ModularCMC platform, supported by state-of-the-art analytical, process development, and cGMP manufacturing capabilities.
High-Touch – Wheeler Bio interfaces with our clients with a partnership mindset rather than a transactional vendor relationship. We are timely and transparent with information, flexible with program design, and offer consistent access to our people and facilities.
Through collaborative conversations and a responsive, iterative Statement of Work (SOW) development process, the Wheeler Bio team leverages its ModularCMC framework to design bespoke, discrete work packages and deliverables customized to the molecule(s) of interest. This high-touch approach ensures alignment on priorities, milestones, timelines, and budget expectations from project inception. Our network of partners complements our core CMC offering, allowing Wheeler to provide a complete solution through fill-finish and regulatory filing support.
ModularCMC™ Platform
ModularCMC is a mammalian cell culture-based drug substance/drug product manufacturing platform that reduces timelines and regulatory risk using QbD (Quality-by-Design) principles early in the drug development life cycle.Our CDMO Services
We offer a comprehensive suite of development capabilities, ranging from cell line expression utilizing a variety of innovative cell line solutions, process and analytical development, cGMP manufacturing and late-stage process characterization.Manufacturing Services
From establishment of cell banks, to scale up of drug substance and drug product manufacturing Wheeler Bio can support biologics manufacturing from discovery to the clinic.Partnership Culture
Values Define Wheeler
Wheeler Bio’s culture is built on core principles that create an environment where relationships, both internally and externally, thrive by cultivating a strong foundation of trust and shared responsibility, enabling teams to align, overcome challenges, and achieve collective success as true partners.
Accountability
Owning and delivering on our commitments and actions
Integrity
Acting with honesty in all situations
Transparency
Open, inclusive, honest and timely communication
Excellence
Delivering work that exceeds expectationsOur Locations
At Wheeler Bio, our Oklahoma based facilities reduce exposure to evolving compliance risk and program disruption. Domestic manufacturing strengthens supply chain security, supports regulatory alignment, and provides the certainty needed to advance with confidence.
Wheeler Manufacturing
The Ziggurat
120 Robert S Kerr Ave.
Oklahoma City, OK 73102
USA
View Google Maps 120 Robert S Kerr Ave.
Oklahoma City, OK 73102
USA
Wheeler Development Laboratories
OU Research Park
655 Research Parkway,
Suite 383
Oklahoma City, OK 73104
USA
View Google Maps 655 Research Parkway,
Suite 383
Oklahoma City, OK 73104
USA
Join Our Team
Advance Science. Create Impact.
We are a growing team that shares a passion for improving patients’ lives by collaborating with thought leaders to develop transformative treatments.